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Antidotes

Antidotes to Common Medications
• Acetaminophen: acetylcysteine or mucomyst • Anticholinesterase: atropine or pralidoxime • Anticholinergics: physostigmine • Antifreeze: fomepizole, ethanol • Benzodiazepines: Romazicon (flumazenil) • Beta-Blocking Agents: Glucagon, epinephrine • Ca++ Channel Blockers: Ca+ chloride, glucagon • Carbon Monoxide (CO): hyperbaric, oxygen • Coumadin: phytonadione or vitamin K • Cyanide: amyl nitrite, sodium nitrite, or sodium thiosulfate • Cyclophosphamide: mesna • Digoxin: Digibind or Digoxin Immune Fab • Dopamine: Rigitine • EPS: Benadryl (diphenhydramine) (Extra Pyramidal Symptoms) • Ethylene Glycol: fomepizole • Fluorouracil: leucovorin calcium • Heroin: Narcan (naloxone) or nalmefene • Heparin: protamine sulfate • Insulin Reaction: IV glucose (D50) • Iron (Fe): deferoxamine • Lead: edetate calcium disodium, dimercaprol, or succimer • Malignant Hyperthermia (MH): dantrolene • Methanol: ethanol • Methotrexate: leucovorin calcium • Narcotics: Narcan (naloxone) or nalmefene • Opioid Analgesics: Narcan (naloxone) or nalmefene • Organophosphate (OPP): atropine, pralidoxime • Potassium (K): Insulin and glucose, NaHCO3, albuterol inhaler, or Kayexalate (sodium polystyrene sulfonate) • Rohypnol: Romazicon (flumazenyl) • TCA (tricyclic antidepressants): physostigmine or NaHCO3 • Tranquilizers-EPS symptoms: Benadryl (diphenhydramine) • Tylenol: acetylcysteine • Warfarin: phytonadione or vitamin K
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